Ankylosing spondylitis is a chronic inflammatory disease of the skeletal system. Especially affecting the spine and Sacro-illiac joint. The early symptom starts with pain in either or both of the SI joint. Later the lower part of spine and /or the upper part of spine gets involved with pain and stiffness. Morning stiffness, mild feverishness are often complained by patients in the initial stage. Gradually it spreads to the other vertebral levels, intercostal joints on chest, resulting to limitted mobility with severe pain, postural abnormalities, buttock pain, hip pain, peripheral arthritis. This being an auto-immune disease and a systemic disease, any coexistence of other disorders involving other joints and systems cant be ruled out. Systemic inflammation is evident as the extra articular manifestations, like Irritable Bowel Syndrome, Acute Uvitis, Psoriasis, cardiovascular disease. In modern medicine the anti-inflammatory drugs, steroids and Biologics are being advised which may coverup the inflammation, pain but they suppress the immune function of the body as well. Patients with presenting complaints of pain in the sacro-iliac joint and stiffness in the spine are advised for tests like HLA B27, CRP to rule out AS. if they come up as positive, an effective treatment could be provided to arrest and reverse at an earier stage itself by observing the diet and lifestyle as practiced in ayurveda for the kind of disturbance in the bio-energies basically all the three dosha and dhatu like Asthi and Majja. The therapies and medications followed in ayurveda here are proven to be effective in reversing the disease. In the initial week, the anti-inflammatory medicines and steroids are withdrawn as the pain subsides and the flexibility in spine and joints improves to a good extent. Further, the posture and the general well being of the patient improves well. The systemic involvement also subsides and patient start leading a normal life without any support of pain killers.

Takayasu's disease, "aortic arch syndrome," "nonspecific aortoarteritis," and "pulseless disease is a form of large vessel granulomatous vasculitis with massive intimal fibrosis and vascular narrowing, most commonly affecting often young or middle-age women of Asian descent, though anyone can be affected. It mainly affects the aorta (the main blood vessel leaving the heart) and its branches, as well as the pulmonary arteries. Females are about 8–9 times more likely to be affected than males. Takayasu's arteritis is similar to other forms of vasculitis, including giant cell arteritis which typically affects older individuals. Due to obstruction of the main branches of the aorta, including the left common carotid artery, the brachiocephalic artery, and the left subclavian artery, Takayasu's arteritis can present as pulseless upper extremities (arms, hands, and wrists with weak or absent pulses on the physical examination). Treatment with certain specific ayurvedic compounds and therapies are found to be significantly effective in arresting the progression of the disease and recuperating the overall health and body function.